Jewett, M. C., Stark, J. C., DeLisa, M. P., & Jaroentomeechai, T. (2020) Method for rapid in vitro synthesis of bioconjugate vaccines via recombinant production of N-glycosylated proteins in prokaryotic cell lysates. US Patent No. 10,829,795.
Patent Applications
Bertozzi, C. R., Stark, J. C., Gray, M. A., & Wisnovsky, S. P. (2021) Bispecific molecules and related compositions and methods. US Provisional Patent Application No. 63170297.
Jewett, M. C., Stark, J. C., DeLisa, M. P., & Jaroentomeechai, T. (published 2018) Cell-free glycoprotein synthesis (CFGpS) in prokaryotic cell lysates enriched with components for glycosylation. US Patent Application Serial No. 62/273,124.
Jewett, M. C., Anderson, M. J., Stark, J. C., & Hodgman, C. E. (published 2017) Methods for activating natural energy metabolism for improved yeast cell-free protein synthesis. US Patent Application Serial No. 15/639,364.
Invited Talks
"Engineering (Glyco)immunology." Chemical Engineering and Materials Science Joint Bioengineering Group Meeting, University of Minnesota, Minneapolis, MN, 13 Oct 2021.
"Understanding and engineering the immune response to glycoconjugates." Cottrell Emerging Scholar Seminar, University of Oregon, Eugene, OR, 29 Jan 2021.
"Cell-free technologies for on-demand glycoprotein biomanufacturing and hands-on biology education." Curie Symposium, University of Washington Institute for Protein Design, Seattle, WA, 21 Nov 2019.
"Using sugars to understand and program the immune system." Hanna H. Gray Fellows Finalist Symposium, Howard Hughes Medical Institute, Chevy Chase, MD, 25 Jun 2019.
Presentations
"Interrogating Siglec immune checkpoints in cancer using interaction proteomics." American Institute of Chemical Engineers Annual Meeting, virtual, 19 Nov 2020 (Oral presentation).
"Cell-free technologies for customizable glycoprotein therapeutic and vaccine production." Mammalian Synthetic Biology Workshop, Evanston, IL, 18 May 2019 (Poster).
"Cell-free technologies for customizable glycoprotein therapeutic and vaccine production." Glycobiology Gordon Research Conference, Lucca (Barga), IT, 9-14 Mar 2019 (Poster). Poster Presentation Award.
"Cell-free technologies for customizable glycoprotein synthesis and point-of-care conjugate vaccine biomanufacturing." Glycobiology Gordon Research Seminar, Lucca (Barga), IT, 9 Mar 2019 (Oral presentation).
"Cell-free technologies for on-demand glycoprotein biomanufacturing." International Conference on Biomolecular Engineering, Newport Beach, CA, 9 Jan 2019 (Oral presentation).
"Cell-free glycoprotein synthesis enables portable, on-demand conjugate vaccine production." Central US Synthetic Biology Workshop, Evanston, IL, 7 Sept 2018 (Oral presentation).
"Customizable, in vitro protein glycosylation for antibacterial and anti-cancer vaccines." American Association for Cancer Research Annual Meeting, Chicago, IL, 17 Apr 2018 (Poster).
"BioBits Bright: A fluorescent synthetic biology education kit." Engineering Biology Research Consortium Retreat, Seattle, WA, 24 March 2018 (Oral presentation and poster).
"Care packages: Developing a cell-free glycoprotein synthesis platform for portable, on-demand antibacterial vaccine production." American Chemical Society National Meeting, New Orleans, LA, 20 Mar 2018 (Oral presentation). Best Presentation Award.
"Portable educational tools for synthetic biology." American Chemical Society National Meeting, New Orleans, LA, 20 Mar 2018 (Poster).
"Mix and match sweets: A cell-free glycoprotein synthesis system for portable, on-demand antibacterial vaccine production." Engineering Biology Research Consortium Retreat, Evanston, IL, 25 Mar 2017 (Oral presentation).
"Mix and match sweets: A cell-free glycoprotein synthesis system for portable, on-demand vaccine production." American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, 14 Nov 2016 (Oral presentation). AIChE Division 15 Oral Presentation Award.
"Mix and match sweets: Modular, coordinated cell-free transcription, translation, and glycosylation of proteins using selectively enriched Escherichia coli cell lysates." Synthetic Biology: Engineering, Evolution, and Design Conference, Chicago, IL, 19 Jul 2016 (Oral presentation).
"Energizing yeast cell-free protein synthesis with glucose metabolism." International Conference on Biomolecular Engineering, Austin, TX, 11-14 Jan 2015 (Poster). 2nd Place Poster Award.
"Energizing yeast cell-free protein synthesis with glucose metabolism." NIH Biotechnology Training Program Biotechnology Day, Northwestern University, Evanston, IL, 06 Oct 2014 (Poster).
"High concentration mAb aggregation, thermal unfolding, and the curious case of mAb A." Pharmaceutical Development Research Forum, Genentech, Inc., South San Francisco, CA, 23 Apr 2013 (Poster).